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2 Spezielle Traumatologie B-2. 7 kb 106 PFUmL Not investigated 109 PFUmL Specific antiviral agent available Yes Difficult No Easy Ease of genetic manipulation Easy Easy Not investigated Immunogenicity Moderate Yes Low No High Yes Low Yes Moderate No Wild-type virus infects nonreplicating cells Virulence of wild-type virus Yes No Slight No No HSV-1 Retrovirus A denovirus A AV Reovirus No-requires transgene for tumor killing 106 PFUmL Low-need to graft packaging cell line High No High No High No Abbreviations: HSV-1, herpes simplex virus-1; AAV, adeno-associated virus; ds, double-stranded; ss, single-stranded.
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