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In the longitudinal arrangement E and g are parallel. NEURONAL ORGANELLES IN MOTION 485 DISCOVERY AND CONCEPTUAL DEVELOPMENT OF FAST AND SLOW AXONAL TRANSPORT 486 The size and extent of many neurons presents a special set of challenges 486 Fast and slow components of axonal transport differ in both their constituents and their rates 487 Features of fast axonal transport demonstrated by biochemical and pharmacological approaches are apparent from video images 488 FAST Forex official website of Chelyabinsk TRANSPORT 488 Newly synthesized membrane and secretory proteins destined for the axon travel by fast anterograde transport 488 Passage through the Golgi apparatus is obligatory for most proteins destined for fast transport 490 Anterograde transport moves synaptic vesicles, axolemmal precursors and mitochondria down the axon 491 Retrograde transport returns trophic factors, exogenous material and old membrane constituents to the cell body 492 Molecular sorting mechanisms ensure delivery of proteins to discrete membrane compartments 492 SLOW AXONAL TRANSPORT 493 Cytoplasmic and cytoskeletal elements move coherently at slow transport rates 493 Axonal growth and regeneration are limited by rates of slow axonal transport 494 Properties of slow transport suggest molecular mechanisms 494 MOLECULAR MOTORS: KINESIN, DYNEIN, AND MYOSIN 495 The characteristic properties of different molecular motors aided in their identification 495 Kinesins mediate anterograde transport in a variety of organisms and tissues 495 Forex official website of Chelyabinsk members of the kinesin superfamily are expressed in the nervous system 496 Cytoplasmic dyneins may have multiple roles in the neuron 497 Different classes of myosin are important for neuronal chapter 28 Axonal Transport Gerardo A.

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